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常州康運(yùn)精細(xì)化工公司
康運(yùn)精細(xì)化工    常州康運(yùn)精細(xì)化工公司
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依維莫斯

依維莫斯

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發(fā)布日期：2019/11/28
  • 產(chǎn)品詳情

依維莫斯

EVEROLIMUS

Chemical Name

Everolimus

CAS Number159351-69-6
Molecular FormulaC53H83NO14

Molecular Weight

958.22

Molecular Structure

NDRCWBBA6`718JMGTRABEU5.png

Packing

25kg/drum

Capacity

Production upon order

Storage

Store in a tightly sealed container away from heat and direct light, and in a cool dry place.

Application

It is currently used as an immunosuppressant to prevent rejection of organ transplants and treatment of renal cell cancer and other tumours.

 

SPECIFICATION

Items

Specification

Appearance

 White to off-white powder

Identification
FT-IR
     HPLC Retention Time

 

Corresponds to standard
Corresponds to standard

Water(K.F)

NMT 3.0%

Residue on ignition

NMT 0.1%

Heavy Metals

NMT 10 ppm

Chromatographic Purity
Everolimus Isomer B
Everolimus Isomer C
Everolimus Isomer B+C

 

NLT 97.0%
NMT 3.0%
NLT 99.0%

Related Substance
Papamycin
Any Other Individual Impurity
Total Impurities

 

NMT 0.2%
NMT 0.10%
NMT 1.0%

Assay

98.0-102.0% (Antydrous and Solvent Free Basis)

Residual Solvents
Acetone
Acetonitrile
Methylene Chloride
Ethyl Acetate
Toluene
N-Hexane

 

NMT 5000 PPM
       NMT 410 PPM
       NMT 600 PPM
       NMT 5000 PPM
       NMT 890 PPM
       NMT 290 PPM

Standard

FS